Five previously unrecognized species of Eugenia L. from the Caribbean lowland forest of Panama are named, described, and assigned IUCN conservation status here: E. arrhaphocalyx Barrie, I. Vergara & McPherson (EN), E. brachyblastiflora Barrie, C. Ramos & O. Ortiz (CR), E. donosoensis Barrie, C. Ramos & O. Ortiz (LC), E. roseola Barrie, C. Ramos & O. Ortiz (LC), and E. roseopetala Barrie, I. Vergara & McPherson (EN).