The new species Hippotis brevistipula M. Calderón is found in northeastern Ecuador and is distinguished from H. triflora Ruiz & Pav. by its usually smaller stipules, longer trichomes, and internally glabrous corollas. The new species H. hirsutissima M. Calderón & C. M. Taylor is found in central Peru and is distinguished from H. brevipes Spruce ex K. Schum. and H. triflora by its longer trichomes on the abaxial surface of the leaves and its longer calyx that splits only along one side.