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1 November 2017 Understanding Reversible Molecular Binding
George P. Smith
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Abstract

Reversible binding between biomolecules—for example, between a cell-sruface receptor such as the insulin receptor and its corresponding natural ligand such as insulin—is central to innumerable physiological transactions. Binding of the dye HABA to egg-white avidin is a simple, reliable, and colorful laboratory model for introducing beginning biology students to the principles underlying reversible binding. They can probe the reaction quantitatively with a spectrophotometer, and model it mathematically using only high-school algebra and a spreadsheet program such as Microsoft Excel.

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George P. Smith "Understanding Reversible Molecular Binding," The American Biology Teacher 79(9), 746-752, (1 November 2017). https://doi.org/10.1525/abt.2017.79.9.746
Published: 1 November 2017
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