Engaging undergraduates in the mechanisms of post-translational modifications lies at the heart of molecular and cell biology education. An important challenge for science educators is developing inclusive and equitable approaches and hands-on demonstrations to clarify post-translational modification mechanisms, such as the protein-splicing mechanism called split inteins. Here, we describe step-by-step assembly of recycled materials to help clarify the molecular action of split inteins in inclusive classroom teaching settings.
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20 October 2020
Doing the Molecular Splits: Hands-On Demonstration Tips to Promote Student Engagement Using Split Inteins in Molecular Biology
Robert M. Kao,
Yan Liu,
Jihong Bai
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The American Biology Teacher
Vol. 82 • No. 7
September 2020
Vol. 82 • No. 7
September 2020
Caenorhabditis elegans
equity
hands-on demonstration
inclusion
split intein
synaptojanin
three-dimensional learning framework