The genus Melchus Lacordaire is redescribed to accommodate Melchus leprosus Lacordaire and four new species as follows: M. gomezi Anderson new species (type locality: Costa Rica, Puntarenas, Las Cruces Biological Station), M. jolyi Anderson new species (type locality: Venezuela, Aragua, Rancho Grande Biological Station), M. onorei Anderson new species (type locality: Ecuador, Napo, Santo Domingo de los Colorados), and M. perplexus Anderson new species (type locality: Bolivia, La Paz, San Jose). The genus Daisya Anderson new genus is described to accommodate Daisya umbratilis (Lacordaire) new combination (not examined) and three new species as follows: D. obriani Anderson new species (type locality: Costa Rica, Puntarenas, Reserva Forestal Golfo Dulce), D. andersonae Anderson new species (type locality: Costa Rica, Puntarenas, Estacion Biologia Las Cruces), and D. huetheri Anderson new species (type locality: Panama, Continental Divide Trail [near La Fortuna]). Only 17 specimens of these two genera are known. Adults were collected in mid-elevation moist tropical forest as well as lowland rain forest but virtually no other information is available about natural history. A key to the seven genera of Neotropical Litosomini is included.