The genus Pluchea on the Arabian Peninsula and Socotra is revised. Seven species are recognized: Pluchea arabica, P. dioscoridis, P. glutinosa, P. indica, P. obovata, P. ovalis and P. sordida. Pluchea indica subsp. yemenensis is described as a subspecies new to science. A key to species and subspecies, a distribution map and illustrations are presented.