Pioneering Mars: Turning the Red Planet Green with the Earth's Smallest Settlers ( http://pioneeringmars.org) provides a partnership model for STEM (science, technology, engineering, and mathematics) learning that brings university scientists together with high school students to investigate whether cyanobacteria from Antarctica could survive on Mars. Funded by NASA, and aligned with the Next Generation Science Standards, this work engages high school students in every aspect of the scientific method, culminating with students designing and implementing experiments in a university lab — experiments that will be replicated on board the International Space Station. Beyond the potential scientific break-throughs it may produce, Pioneering Mars provides a STEM education model for project-based learning using university and school partnerships. Our team consists of a university marine science professor, a STEM education researcher, four high school science teachers, and 85 high-achieving students. The model can easily transfer to leaders and learners across the United States who will be able to replicate and extend this effort in their own educational settings.

In a companion article, I discussed recent developments in genetics and the inadequacies of eight common claims made by biology teachers, followed by suggested replacement language for those statements. In the present article, I address nine more claims, about such topics as whether or not most human characteristics are inherited as simple Mendelian traits (determined by one gene with a dominant and a recessive allele), problems with the Central Dogma of Biology, misunderstandings about the inheritance of traits such as eye color, the relative importance of genetics versus the environment, “genes FOR” language, and junk DNA.

One of the key aspects of natural selection is competition, yet the concept of competition is not necessarily emphasized in explanations of natural selection. Because of this, we developed an activity for our class that focuses on competition and provides an example of the effects of competition on natural selection. This hands-on activity models the field study completed by David Lack on Darwin's finches. By using this historical study, we also give students an example of the nature-of-science concept of multiple methods. Although this activity was created for a college introductory biology course, it is appropriate for high school. We also provide an additional objective for upper-level ecology and evolution courses.

We describe a field-based lizard project we did with high school students as a part of our summer Herpetological Research Experiences. We describe data collection on lizards captured, identified, and marked as a part of our mark—recapture study. We also describe other lizard projects that are ongoing in the United States and provide resources for teachers to help them start their own field-based science projects. Our work with lizards focuses on fieldwork but also includes classroom components with captive-bred and wild-captured animals. Information on organizations that focus on lizards is provided, including several citizen science opportunities.

In this practice-based lab, students are provided with four Olympic athlete profiles and simulated blood and urine samples to test for illegal substances and blood-doping practices. Throughout the course of the lab, students design and conduct a testing procedure and use their results to determine which athletes won their medals fairly. All of the materials, which simulate the blood, urine, and testing compounds, are available at the grocery store. This real-world problem engages students to think about blood doping, hormones associated with red-blood-cell production, and detection techniques employed by the World Anti-Doping Agency. The Olympics, as well as the news coverage of Lance Armstrong's admission to blood doping in 2013, makes this lab more relevant to students' lives, which is supported by our students' reactions to the lab.

The AAAS Vision and Change report (2011) recommends incorporating student research experiences into the biology curriculum at the undergraduate level. This article describes, in detail, how Zea mays (corn) cultivars were used as a model for a hypothesis-driven short-term research project in an introductory biology course at a small Midwestern university. During the course of this project, student groups generated a research question and hypothesis, designed an experiment, collected data, and reported their findings in a paper modeled after the primary literature. Throughout the project, students experienced first hand the obstacles and accomplishments associated with the process of scientific research and gained a greater understanding of plant biology. By demonstrating biology as a dynamic field centered around hypothesis generation and experimentation, the authors observed an increase in student dedication, interest, and enthusiasm for the course.

This article contains an original 5E lesson plan developed from conservation genetics research on the giant North American hellbender salamander, Cryptobranchus alleganiensis alleganiensis. The lesson plan provides background information on the hellbender, reviews basic genetics, and exposes students to the scientific process that is used during PCR (polymerase chain reaction) and the analysis of microsatellites in order to calculate allele and genotype frequencies for understanding genetic variability. Once completing the lesson, students should make the connection between molecular research and conservation of a rare, cryptic, and interesting species.

This article explains four kinds of inquiry exercises, different in purpose, for teaching advanced-level high school and college students the hypothetico-deductive (H-D) method. The first uses a picture of a river system to convey the H-D methods logic. The second has teams of students use the H-D method: their teacher poses a hypothesis drawn from a research article the students have not seen and asks them to design an H-D test of it. Later they read the article and compare their designs with its. The third exercise extends this; when economically practical, the class may experimentally test the best of its designs. Finally, an Internet/library exercise lets students inquire into the history of the H-D method.

“Biology Myth-Killers” is an activity designed to identify and correct common misconceptions for high school and college introductory biology courses. Students identify common myths, which double as biology misconceptions, and use appropriate sources to share the “truth” about the myths. This learner-centered activity is a fun and engaging way to correct misconceptions and prepare students to overcome other important misconceptions.

Measuring plant stem growth over time is a simple activity commonly used to introduce concepts in growth and development in plant biology (Reid & Pu, 2007). This Quick Fix updates the activity and incorporates a real-world application: students consider possible effects of soil substrate and sunlight conditions on plant growth without needing access to costly supplies. Although written for undergraduates, the activity could be adapted for secondary students.